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Sunday, 12 January 2020

Silent Miscarriage (Things We Don’t Know about Pregnancy Series #11)

Miscarriage is a common medical complication that leads to the loss of a pregnancy before 23 weeks, and affects 1 in 4 women during their reproductive lifetime. Depending on how early or late it happens, it can have bigger or smaller impacts on a woman’s physical and mental health.

But why does it happen? Is it mostly to do with lifestyle, or genetics? Is there something you can do to prevent it? And how can we get early warnings of silent miscarriages – the ones you never even knew had happened?


If you’ve ever been pregnant – miscarriage or not – you’ll probably have wondered about these things, and worried about them, as I have. Whilst the chance of miscarriage drops off rapidly with time, stillbirth and postnatal foetal death are still classed as late pregnancy losses, and do happen from time to time, meaning there is no good time to truly forget about it.

Chances of miscarriage drop as pregnancy progresses. © TWDK. Data from: https://datayze.com/miscarriage-chart.php

Saturday, 4 January 2020

The Thalidomide Scandal (Things We Don’t Know about Pregnancy Series #10)

In 1953, a new drug was made, and by 1957 it was on the market. In the six years that followed, over 10,000 children in 46 countries were born with congenital deformities[1]. The disaster was known as the thalidomide scandal, and led to serious reforms in drug regulation and monitoring worldwide.

What happened?

Thalidomide was prescribed for insomnia, anxiety, asthma, hypertension, migraine, and morning sickness. Doctors thought that it was very safe because taking an overdose simply cast the drinker into a prolonged sleep – and did not cause death. It was also non-addictive. Nobody tested it in pregnant women or animals.

Then, in 1961, two doctors independently called out statistically high numbers of congenital abnormalities in “thalidomide babies” – 20% where the normal rate is 1.5% (or a bit higher, depending on your source)[2].

Thalidomide babies. Image via Wikipedia Commons.